The first operational CH-149 flight occurred in 2002 when a Cormorant of 442 Squadron performed a medical evacuation from a merchant ship 200 km (110 nmi) offshore in Hecate Strait. An even more dramatic demonstration of Cormorant capabilities occurred in late 2002 when a 103 Squadron CH-149 successfully flew a 1,200 km round-trip rescue mission to a container ship off Newfoundland. Two refuelling stops at the Hibernia oil platform were required.

On October 25, 2006, a search and rescue crew from 442 Squadron in Comox, B.C. conducted a rescue from the side of a cliff in a box canyon with the CH-149 Cormorant which Canadian Forces Captain Sean Morris described as "pretty much the worst situation I've been in my entire life." Captain Morris and his colleagues received international recognition for the rescue as the first Canadian winner of the Prince Phillip Helicopter Rescue Award issued by the Guild of Air Pilots and Air Navigators in the UK

In August 2010, the Canadian Forces fleet of 14 CH-149 Cormorants passed 40,000 operational hours. The fleet had a higher flying rate than any other AW101 fleet and Cormorant 901, currently stationed at Canadian Forces Base Comox with 442 Squadron, has the highest number of airframe hours on any of the AW101s anywhere in the world. The worldwide fleet of 190 Aw101 helicopters had achieved in excess of 200,000 flight hours in Canada, UK, Italy, Denmark, Portugal, and Japan.

In June 2011, several US VH-71, which are also based upon the AW101, were purchased by Canada to be used as spare parts for the CH-149 fleet

Twee uitvoeringen mogelijk;